Para-KDL in HIV co-infection: case report of a rare visceral-cutaneous leishmaniasis syndrome

The co-existence of active VL and PKDL can make diagnosis difficult, potentially leading to misdiagnosis and treatment, particularly in immunocompromised patients. The simultaneous occurrence of VL and PKDL-like skin lesions requires heightened clinical suspicion, especially in endemic regions. Delayed or misdiagnosed cases may lead to significant morbidity. Further research is needed to understand the pathophysiology, immune response, and optimal treatment strategies for para-KDL in HIV-infected individuals.

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Journal
AIDS Research and Therapy
Published
2025-12-09
DOI
https://doi.org/10.1186/s12981-025-00821-w
Primary Topic
Research on Leishmaniasis Studies
Type
article
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article

Para-KDL in HIV co-infection: case report of a rare visceral-cutaneous leishmaniasis syndrome

Safoura Shakoei, Farideh Jafari‐Raddani, Malihe Hasannezhad, Alireza Ghanadan et al.
AIDS Research and Therapy
Research on Leishmaniasis Studies
article

Para-KDL in HIV co-infection: case report of a rare visceral-cutaneous leishmaniasis syndrome

Safoura Shakoei, Farideh Jafari‐Raddani, Malihe Hasannezhad, Alireza Ghanadan, Zahra Valizadeh, Sara Ghaderkhani, Ladan Abbasian
article en

Abstract

The co-existence of active VL and PKDL can make diagnosis difficult, potentially leading to misdiagnosis and treatment, particularly in immunocompromised patients. The simultaneous occurrence of VL and PKDL-like skin lesions requires heightened clinical suspicion, especially in endemic regions. Delayed or misdiagnosed cases may lead to significant morbidity. Further research is needed to understand the pathophysiology, immune response, and optimal treatment strategies for para-KDL in HIV-infected individuals.

AIDS Research and TherapyVol. 23(1)
Imam Khomeini Hospital (IR), Iranian Institute for Health Sciences Research (IR), Iranian Center for Quantum Technologies (IR), Razi Hospital (IR), Tehran University of Medical Sciences (IR)
Openalex Percentile: Top 50%
Research on Leishmaniasis Studies
DOIOpen Access PDFOpenAlex
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Para-KDL in HIV co-infection: case report of a rare visceral-cutaneous leishmaniasis syndrome — Safoura Shakoei, Farideh Jafari‐Raddani, et al. · AIDS Research and Therapy (2025) | TGRS Research Map | TGRS