Synthesis of new tetra- and pentacyclic, methylenedioxy- and ethylenedioxy-substituted derivatives of the dibenzo[ <i>c</i> , <i>f</i> ][1,2]thiazepine ring system
New tetra- and pentacyclic derivatives of the dibenzo[<i>c</i>,<i>f</i>][1,2]thiazepine ring system have been synthesized. The target compounds contain methylenedioxy or ethylenedioxy substituents linked to the benzene ring. The key step for the construction of the ring systems has been implemented by an intramolecular Friedel-Crafts cyclization. Altogether eight new ring systems are described here, five of them are also characterized by single-crystal X-ray diffraction.
Authors
- Lóránd Kiss (ORCID: https://orcid.org/0000-0003-2346-9816)
- András Dancsó (ORCID: https://orcid.org/0000-0001-8460-217X)
- Balázs Volk (ORCID: https://orcid.org/0000-0002-2019-1874)
- Mária Tóthné Lauritz
- Gyula Simig (ORCID: https://orcid.org/0000-0002-2569-6476)
- Gábor Berecz
Institutions
- Egis Pharmaceuticals (Hungary) (HU)
- HUN-REN Research Centre for Natural Sciences (HU)
Publication Details
- Journal
- Beilstein Journal of Organic Chemistry
- Published
- 2025-12-09
- DOI
- https://doi.org/10.3762/bjoc.21.205
- Primary Topic
- Organic and Inorganic Chemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Hungarian Scientific Research Fund
- Nemzeti Kutatási Fejlesztési és Innovációs Hivatal
- Nemzeti Kutatási, Fejlesztési és Innovaciós Alap
- National Research, Development and Innovation Office