A Semantic Framework for the Contextual Interpretation of ADHD Symptom Manifestations

Attention Deficit Hyperactivity Disorder is a neurodevelopmental disorder whose manifestations vary significantly depending on the context. This situational variability poses major challenges for assessing and understanding symptoms, particularly outside clinical environments. In this work, we propose a framework that integrates a contextual vision to enrich medical information. The framework is composed of three main components: a modular ontology that formalizes both medical and contextual dimensions of ADHD; a multi-agent system powered by large language models for automatically extracting and populating knowledge from heterogeneous data sources; and a clinical rule-based reasoning mechanism capable of inferring high-level interpretations from instantiated data. Experimental results demonstrate the framework’s ability to generate accurate, context-sensitive interpretations of symptom manifestations. This approach lays the groundwork for more personalized, explainable, and context-aware patient monitoring, with promising applications in intelligent healthcare systems.

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Published
2025-12-09
DOI
https://doi.org/10.1145/3731443.3771356
Primary Topic
Machine Learning in Healthcare
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article
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article

A Semantic Framework for the Contextual Interpretation of ADHD Symptom Manifestations

Imen Megdiche, Jérôme Marquet-Doléac, Lotfi Chaâri, Abdel‐Rahman H. Tawil et al.
Machine Learning in Healthcare
article

A Semantic Framework for the Contextual Interpretation of ADHD Symptom Manifestations

Imen Megdiche, Jérôme Marquet-Doléac, Lotfi Chaâri, Abdel‐Rahman H. Tawil, Konstantinos Vlachos, Ibrahim Traore
article en

Abstract

Attention Deficit Hyperactivity Disorder is a neurodevelopmental disorder whose manifestations vary significantly depending on the context. This situational variability poses major challenges for assessing and understanding symptoms, particularly outside clinical environments. In this work, we propose a framework that integrates a contextual vision to enrich medical information. The framework is composed of three main components: a modular ontology that formalizes both medical and contextual dimensions of ADHD; a multi-agent system powered by large language models for automatically extracting and populating knowledge from heterogeneous data sources; and a clinical rule-based reasoning mechanism capable of inferring high-level interpretations from instantiated data. Experimental results demonstrate the framework’s ability to generate accurate, context-sensitive interpretations of symptom manifestations. This approach lays the groundwork for more personalized, explainable, and context-aware patient monitoring, with promising applications in intelligent healthcare systems.

Birmingham City University (GB), Université Toulouse III - Paul Sabatier (FR), Inserm (FR), Université Fédérale de Toulouse Midi-Pyrénées (FR), Université Toulouse-I-Capitole (FR), Institut de Recherche en Informatique de Toulouse (FR), Université Toulouse - Jean Jaurès (FR), Institut Polytechnique de Bordeaux (FR)
Openalex Percentile: Top 79%
Machine Learning in Healthcare
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A Semantic Framework for the Contextual Interpretation of ADHD Symptom Manifestations — Imen Megdiche, Jérôme Marquet-Doléac, et al. · (2025) | TGRS Research Map | TGRS