Discrepancy between international normalized ratio measurements in a heterozygous carrier of F10:p.Gly244Arg with recurrent venous thromboembolism: a case report
Genetic variants in <i>F10</i> may also interfere with INR or prothrombin time measurements when different thromboplastins are used. This case illustrates that discrepancies in INR measurements with different thromboplastins should prompt consideration of genetic variants in <i>F10</i> and <i>F7</i> to ensure sufficient anticoagulant VKA treatment.
Authors
- Nikolaj Julian Skrøder Nytofte (ORCID: https://orcid.org/0009-0004-7076-6682)
- Emil List Larsen (ORCID: https://orcid.org/0000-0002-0676-0858)
Institutions
- Slagelse Hospital (DK)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1016/j.rpth.2025.103298
- Primary Topic
- Blood Coagulation and Thrombosis Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00