Machine learning–based binary classification of elevated HbA1c (≥6.5 %) for risk assessment

The greatest predictor was age, which was positively correlated with elevated HbA1c levels, whereas HDL had a protective impact. The addition of VitaminD3, VDL, and GPT implies that indicators of liver and metabolic function have a major role in the variability of HbA1c. These results demonstrate how normal clinical and demographic data may be incorporated into predictive models for early diabetes risk assessment, enabling more individualized medical care and bettering patient outcomes.

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Publication Details

Journal
Metabolism Open
Published
2025-12-09
DOI
https://doi.org/10.1016/j.metop.2025.100428
Primary Topic
Diabetes, Cardiovascular Risks, and Lipoproteins
Type
article
Field-Weighted Citation Impact
0.00
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article

Machine learning–based binary classification of elevated HbA1c (≥6.5 %) for risk assessment

Azhin M. Khudhur, Dler Hussein Kadir, Hewir Abdulqadir Khidir
Metabolism Open
Diabetes, Cardiovascular Risks, and Lipoproteins
article

Machine learning–based binary classification of elevated HbA1c (≥6.5 %) for risk assessment

Azhin M. Khudhur, Dler Hussein Kadir, Hewir Abdulqadir Khidir
article en

Abstract

The greatest predictor was age, which was positively correlated with elevated HbA1c levels, whereas HDL had a protective impact. The addition of VitaminD3, VDL, and GPT implies that indicators of liver and metabolic function have a major role in the variability of HbA1c. These results demonstrate how normal clinical and demographic data may be incorporated into predictive models for early diabetes risk assessment, enabling more individualized medical care and bettering patient outcomes.

Metabolism OpenVol. 29
Cihan University-Erbil (IQ), Salahaddin University-Erbil (IQ)
Openalex Percentile: Top 49%
Diabetes, Cardiovascular Risks, and Lipoproteins
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