Carvacrol ameliorates cyclophosphamide-induced rat premature ovarian failure and uterine fibrosis via regulating PI3K/AKT/FOXO3a signaling pathway
Hence, it could be concluded that Carva could preserve rat ovarian function from the degenerative impacts of Cyclo treatment by lessening the oxidative and apoptotic insult via regulating the PI3K/AKT/FOXO3a pathways in the ovarian tissues, along with successful attenuation of uterine fibrosis.
Authors
- Mohamed Sayed (ORCID: https://orcid.org/0000-0002-9547-9039)
- Zeinab A. El‐Gendy (ORCID: https://orcid.org/0000-0002-5024-2337)
- Seham Samir Soliman (ORCID: https://orcid.org/0000-0001-8022-1337)
- Sara M. Baraka
Institutions
- National Research Centre (EG)
Publication Details
- Journal
- Journal of Ovarian Research
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1186/s13048-025-01880-3
- Citations
- 1
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 1.88