The association between intrahepatic malignant tumors and hepatitis B-related pathological cirrhosis: a retrospective cohort study

This study developed a predictive model for HCC based on age, WBC, C4, and CIV in patients with HBV-related cirrhosis. The model effectively predicted the risk of HCC and provided a reference for clinical intervention. Despite limitations in sample size, the model exhibited robust predictive performance and clinical applicability. Future work should validate the model in multicenter studies and integrate multi-omics data to develop a more comprehensive predictive system.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-12-09
DOI
https://doi.org/10.3389/fmed.2025.1618715
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

The association between intrahepatic malignant tumors and hepatitis B-related pathological cirrhosis: a retrospective cohort study

Weijia Lin, Wei-Ting Lu, Xiaofei Liu, Zhanqing Zhang et al.
Frontiers in Medicine
Liver Disease Diagnosis and Treatment
article

The association between intrahepatic malignant tumors and hepatitis B-related pathological cirrhosis: a retrospective cohort study

Weijia Lin, Wei-Ting Lu, Xiaofei Liu, Zhanqing Zhang, Dan Huang, Fengping Li
article en

Abstract

This study developed a predictive model for HCC based on age, WBC, C4, and CIV in patients with HBV-related cirrhosis. The model effectively predicted the risk of HCC and provided a reference for clinical intervention. Despite limitations in sample size, the model exhibited robust predictive performance and clinical applicability. Future work should validate the model in multicenter studies and integrate multi-omics data to develop a more comprehensive predictive system.

Frontiers in MedicineVol. 12
Shanghai Public Health Clinical Center (CN)
Openalex Percentile: Top 49%
Liver Disease Diagnosis and Treatment
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