The association between intrahepatic malignant tumors and hepatitis B-related pathological cirrhosis: a retrospective cohort study
This study developed a predictive model for HCC based on age, WBC, C4, and CIV in patients with HBV-related cirrhosis. The model effectively predicted the risk of HCC and provided a reference for clinical intervention. Despite limitations in sample size, the model exhibited robust predictive performance and clinical applicability. Future work should validate the model in multicenter studies and integrate multi-omics data to develop a more comprehensive predictive system.
Authors
- Weijia Lin
- Wei-Ting Lu (ORCID: https://orcid.org/0000-0002-1405-4806)
- Xiaofei Liu (ORCID: https://orcid.org/0000-0001-7830-6219)
- Zhanqing Zhang (ORCID: https://orcid.org/0000-0001-7709-9027)
- Dan Huang (ORCID: https://orcid.org/0000-0002-0956-780X)
- Fengping Li (ORCID: https://orcid.org/0000-0001-6508-387X)
Institutions
- Shanghai Public Health Clinical Center (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-12-09
- DOI
- https://doi.org/10.3389/fmed.2025.1618715
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00