Pharmacokinetics and pharmacodynamics of cannabigerol (CBG) in the C57BL/6Crl mouse
Our data reveal that CBG was not intoxicating, even when accounting for the route of administration and blood concentration. Our findings support previous reports that CBG is not intoxicating and reveal that even if CBG were present at sufficiently high concentrations in cannabis products, it would not produce intoxicating effects like those of THC.
Authors
- Roger Y. Andres
- Ayat Zagzoog
- Deborah L. Michel (ORCID: https://orcid.org/0000-0001-5161-8677)
- Robert B. Laprairie (ORCID: https://orcid.org/0000-0002-9994-433X)
- Jane Alcorn (ORCID: https://orcid.org/0000-0002-3473-2635)
- Kenzie Halter
- Andy Kim (ORCID: https://orcid.org/0000-0001-6551-2881)
- Ngan Tran Ha
- A. Jones
Institutions
- University of Saskatchewan (CA)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-12-09
- DOI
- https://doi.org/10.3389/fphar.2025.1672098
- Primary Topic
- Cannabis and Cannabinoid Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- College of Pharmacy and Nutrition, University of Saskatchewan