Comparison of currently common neoadjuvant therapy strategies for rectal cancer: a three-arm retrospective study
Both TNT and PD-1 combination therapy demonstrated higher tumor regression and pCR rates compared with nCRT, suggesting enhanced local tumor control. However, improvements in rectal MRI accuracy and gut microbiome research are needed to enhance precision in diagnostics and therapy.
Authors
- Yihan Lu (ORCID: https://orcid.org/0000-0003-4651-9433)
- Ganbin Li (ORCID: https://orcid.org/0000-0002-2576-1100)
- Xiaoyuan Qiu (ORCID: https://orcid.org/0000-0003-1494-9068)
- Xiao Zhang (ORCID: https://orcid.org/0000-0002-9244-9344)
- Guole Lin (ORCID: https://orcid.org/0000-0001-6225-3028)
- Yuxin Liu (ORCID: https://orcid.org/0000-0002-4115-3658)
- An Yang (ORCID: https://orcid.org/0000-0002-0629-9440)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-12-09
- DOI
- https://doi.org/10.3389/fcimb.2025.1545195
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00