Sex differences in stress-modulated cocaine vulnerability: female rodents are more sensitive to the effects of stress exposure at different developmental stages
There is growing evidence that women and female rodents are more vulnerable to the behavioral and neurochemical changes that characterize cocaine addiction. The influence of sex should be considered in research and in the selection of strategies for preventing and treating CUD, including those targeting stress reduction.
Authors
- María Pilar García-Pardo (ORCID: https://orcid.org/0000-0003-2730-0145)
- Maria Ángeles Martínez-Caballero
- M. Carmen Arenas (ORCID: https://orcid.org/0000-0003-2201-6882)
- Carmen Manzanedo (ORCID: https://orcid.org/0000-0002-3887-9589)
- Claudia Calpe-López (ORCID: https://orcid.org/0000-0001-9926-8485)
- M.A. Aguilar (ORCID: https://orcid.org/0000-0002-1935-6619)
Institutions
- Universitat de València (ES)
- Heidelberg University (DE)
- Universidad de Zaragoza (ES)
- University Hospital Heidelberg (DE)
- Central Institute of Mental Health (DE)
Publication Details
- Journal
- Frontiers in Behavioral Neuroscience
- Published
- 2025-12-09
- DOI
- https://doi.org/10.3389/fnbeh.2025.1689548
- Primary Topic
- Neurotransmitter Receptor Influence on Behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universitat de València
- Agencia Estatal de Investigación