Organ-specific role of neutrophil extracellular traps in shaping the postoperative thrombo-inflammatory niche in pancreatic ductal adenocarcinoma: a multi-model machine learning and mechanistic study
In patients with PDAC, higher NETs levels are correlated with an increased risk of developing PVT and are indicative of poor prognosis. Assessment of Cit-H3 and D-dimer levels may aid clinicians in predicting PVT.
Authors
- Jincan Huang (ORCID: https://orcid.org/0009-0003-4548-1266)
- Shaocheng Lyu (ORCID: https://orcid.org/0000-0002-2757-7868)
- Jing Wang (ORCID: https://orcid.org/0000-0002-9084-9985)
- Di Wang (ORCID: https://orcid.org/0000-0002-7202-2474)
- Ren Lang (ORCID: https://orcid.org/0000-0001-8995-8749)
- Songping Cui
Institutions
- Tianjin First Center Hospital (CN)
- Beijing Chao-Yang Hospital, Capital Medical University (CN)
- Massachusetts General Hospital (US)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-12-09
- DOI
- https://doi.org/10.3389/fimmu.2025.1728391
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00