Case Report: Post-LASIK exacerbation of granular corneal dystrophy type 2: a familial case with TGFBI mutation
LASIK surgery significantly accelerates granular corneal dystrophy type 2 progression through multiple pathophysiological mechanisms. Comprehensive preoperative assessment incorporating genetic screening for <i>TGFBI</i> mutations is essential to identify and exclude contraindicated candidates for refractive surgery.
Authors
- Xuanjun Zhang (ORCID: https://orcid.org/0000-0001-6452-1778)
- Longhao Kuang
- Jing-Jing Su
- Bao-tao Lin
- Ping Guo (ORCID: https://orcid.org/0000-0003-0096-4814)
- Qing Zhan (ORCID: https://orcid.org/0000-0002-3536-7844)
- Yufang Wang
Institutions
- University Town of Shenzhen (CN)
- Southern Medical University Shenzhen Hospital (CN)
- Guangzhou Medical University (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-12-09
- DOI
- https://doi.org/10.3389/fmed.2025.1721130
- Primary Topic
- Corneal surgery and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Sanming Project of Medicine in Shenzhen
- Basic and Applied Basic Research Foundation of Guangdong Province