Impact of red blood cell transfusion volume on long-term mortality after transcatheter aortic valve replacement

Elevated transfusion volumes significantly correlate with increased long-term mortality risk in transfused TAVR recipients, primarily mediated by life-threatening hemorrhagic complications. These findings underscore the importance of implementing bleeding mitigation strategies to minimize transfusion requirements and improve clinical outcomes.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2025-12-09
DOI
https://doi.org/10.3389/fcvm.2025.1612385
Primary Topic
Blood transfusion and management
Type
article
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article

Impact of red blood cell transfusion volume on long-term mortality after transcatheter aortic valve replacement

Zhen‐Gang Zhao, Yuanweixiang Ou, Yi Zhang, Mao Chen et al.
Frontiers in Cardiovascular Medicine
Blood transfusion and management
article

Impact of red blood cell transfusion volume on long-term mortality after transcatheter aortic valve replacement

Zhen‐Gang Zhao, Yuanweixiang Ou, Yi Zhang, Mao Chen, Yong Peng, Weiya Li, Jiafu Wei, Shiqin Peng, Yuan Feng
article en

Abstract

Elevated transfusion volumes significantly correlate with increased long-term mortality risk in transfused TAVR recipients, primarily mediated by life-threatening hemorrhagic complications. These findings underscore the importance of implementing bleeding mitigation strategies to minimize transfusion requirements and improve clinical outcomes.

Frontiers in Cardiovascular MedicineVol. 12
Sichuan University (CN), West China Hospital of Sichuan University (CN)
Openalex Percentile: Top 60%
Blood transfusion and management
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Impact of red blood cell transfusion volume on long-term mortality after transcatheter aortic valve replacement — Zhen‐Gang Zhao, Yuanweixiang Ou, et al. · Frontiers in Cardiovascular Medicine (2025) | TGRS Research Map | TGRS