Association of intestinal barrier impairment with symptom severity and washed microbiota transplantation outcomes in atopic dermatitis patients

This study confirms significant intestinal barrier dysfunction in AD and demonstrates the potential clinical efficacy of WMT. The strong, uncorrected correlations suggest that pre-treatment D-lactate level warrants further investigation as a candidate biomarker for predicting WMT response. The clinical benefits occurred alongside a restructuring of the gut microbiota.