Phoxim induces neurotoxicity and intestinal damage in Caenorhabditis elegans
Our results indicate that phoxim exposure reduces dopaminergic neuron integrity, accelerates Aβ-induced paralysis, and damages intestinal cells through inhibition of autophagy in <i>C. elegans</i>.
Authors
- Wei Zou (ORCID: https://orcid.org/0000-0001-6492-2790)
- Qi Wang (ORCID: https://orcid.org/0000-0002-1588-9047)
- Hua Bai (ORCID: https://orcid.org/0000-0003-1979-3760)
- Mengyuan Zhang (ORCID: https://orcid.org/0009-0009-5279-3712)
- Xin Zhao
Institutions
- Kunming Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-12-09
- DOI
- https://doi.org/10.3389/fphar.2025.1657527
- Citations
- 1
- Primary Topic
- Genetics, Aging, and Longevity in Model Organisms
- Type
- article
- Field-Weighted Citation Impact
- 0.95