Temporal changes in tongue color during immune checkpoint inhibitor therapy in patients with non-small-cell lung cancer: a prospective observational study using digital tongue diagnosis
Digital TD diagnosis, particularly monitoring tongue lightness changes, may provide a valuable noninvasive prognostic tool for patients with NSCLC undergoing ICI therapy. It offers information for both PFS and OS, potentially complementing current biomarkers for cancer immunotherapy.
Authors
- Ji Woong Son (ORCID: https://orcid.org/0000-0001-5951-5058)
- Mi Mi Ko (ORCID: https://orcid.org/0000-0002-5758-4655)
- Mi-Kyung Jeong (ORCID: https://orcid.org/0000-0002-0239-0159)
- Seung Hun Jang (ORCID: https://orcid.org/0000-0001-5457-5780)
- Chang‐Min Choi (ORCID: https://orcid.org/0000-0002-2881-4669)
- Woosu Choi (ORCID: https://orcid.org/0000-0003-3924-8225)
- Seung Hyeun Lee (ORCID: https://orcid.org/0000-0002-7666-313X)
- Sung Yong Lee (ORCID: https://orcid.org/0000-0002-8693-5792)
- Seung Joon Kim (ORCID: https://orcid.org/0000-0003-4836-8958)
- In‐Jae Oh (ORCID: https://orcid.org/0000-0003-4837-1321)
- Seong Hoon Yoon (ORCID: https://orcid.org/0000-0002-2075-4702)
- Jun Hyeok Lim (ORCID: https://orcid.org/0000-0001-5515-737X)
- Eunbyul Cho (ORCID: https://orcid.org/0000-0002-1540-6447)
- Jong Gwon Choi
- Tae Won Jang
Institutions
- Ulsan College (KR)
- Korea University Medical Center (KR)
- Sacred Heart Hospital (IE)
- Kosin University Gospel Hospital (KR)
- Asan Medical Center (KR)
- Kyung Hee University (KR)
- University of Ulsan (KR)
- Korea Institute of Oriental Medicine (KR)
- St. Mary's Hospital (US)
- Konyang University Hospital (KR)
- Sacred Heart Hospital (US)
- Chonnam National University Hwasun Hospital (KR)
- Pusan National University Yangsan Hospital (KR)
- Kyung Hee University Hospital at Gangdong (KR)
- Inha University Hospital (KR)
- Hallym University Sacred Heart Hospital (KR)
- The Catholic University of Korea Seoul St. Mary's Hospital (KR)
- Wonkwang University (KR)
- Catholic University of Korea (KR)
Publication Details
- Journal
- Oncology Reviews
- Published
- 2025-12-09
- DOI
- https://doi.org/10.3389/or.2025.1697252
- Primary Topic
- Advanced Chemical Sensor Technologies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Korea Institute of Oriental Medicine