Continuous Hemodialysis in Severe Lithium Intoxication: A Successful Case Management in a 67-Year-Old Woman

Lithium toxicity is a potentially life-threatening condition characterized by neurological, gastrointestinal, and cardiovascular manifestations. Although intermittent hemodialysis (IHD) is the standard of care for severe lithium poisoning, continuous hemodialysis (CHD) or continuous renal replacement therapy (CRRT) may be preferred in cases of hemodynamic instability or severe neurological symptoms. We report a case of severe lithium intoxication in a 67-year-old woman successfully treated with CHD. Treatment was initiated before the serum lithium concentration became available. Despite marked neurological symptoms, including altered consciousness and tremors, CHD achieved gradual clinical improvement and full recovery without symptom recurrence.

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Journal
Cureus
Published
2025-12-08
DOI
https://doi.org/10.7759/cureus.98769
Citations
1
Primary Topic
Bipolar Disorder and Treatment
Type
article
Field-Weighted Citation Impact
1.47
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article

Continuous Hemodialysis in Severe Lithium Intoxication: A Successful Case Management in a 67-Year-Old Woman

Hideaki Imanaka, Masaatsu Kuwahara
1 citations
Cureus
Bipolar Disorder and Treatment
1.47
article

Continuous Hemodialysis in Severe Lithium Intoxication: A Successful Case Management in a 67-Year-Old Woman

Hideaki Imanaka, Masaatsu Kuwahara
article en
1 citations

Abstract

Lithium toxicity is a potentially life-threatening condition characterized by neurological, gastrointestinal, and cardiovascular manifestations. Although intermittent hemodialysis (IHD) is the standard of care for severe lithium poisoning, continuous hemodialysis (CHD) or continuous renal replacement therapy (CRRT) may be preferred in cases of hemodynamic instability or severe neurological symptoms. We report a case of severe lithium intoxication in a 67-year-old woman successfully treated with CHD. Treatment was initiated before the serum lithium concentration became available. Despite marked neurological symptoms, including altered consciousness and tremors, CHD achieved gradual clinical improvement and full recovery without symptom recurrence.

CureusVol. 17(12)
Takarazuka City Hospital (JP)
Openalex Percentile: Top 13%
Bipolar Disorder and Treatment
1.47
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