Citywide community-based colorectal cancer screening in urban Shanghai: age and sex variations in risk mitigation from 1973 to 2020
The program significantly reduced CRC mortality, particularly in females and the elderly, though incidence trends varied by age. Despite a significant reduction in mortality, the observed stability in overall CRC incidence is an expected finding in the initial years of a screening program. This pattern is largely due to increased detection of prevalent pre-existing cases during the first screening round, which may temporarily offset the decline in incident cases.
Authors
- Yan Shi (ORCID: https://orcid.org/0000-0001-9777-8836)
- Yi Pang (ORCID: https://orcid.org/0000-0001-7275-4563)
- Xiaocong Zhang (ORCID: https://orcid.org/0000-0003-0897-5796)
- Yongmei Xiang
- Lei Chen (ORCID: https://orcid.org/0009-0003-4906-5163)
- Qi Li (ORCID: https://orcid.org/0000-0002-8282-4884)
- Yangming Gong
- Kai Gu (ORCID: https://orcid.org/0000-0002-1028-1868)
- Jianming Dou
- Mengyin Wu (ORCID: https://orcid.org/0000-0002-4132-3602)
- Liang Shi (ORCID: https://orcid.org/0000-0002-9392-4274)
- Peng Peng (ORCID: https://orcid.org/0000-0002-4643-6198)
- Chunxiao Wu
Institutions
- Shanghai Municipal Center For Disease Control Prevention (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-12-09
- DOI
- https://doi.org/10.3389/fonc.2025.1707133
- Primary Topic
- Colorectal Cancer Screening and Detection
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science and Technology Major Project