The microbiome exists in the neuroretina and choroid in normal conditions and responds rapidly to retinal injury

The neuroretina and RPE/choroid have diverse microbiomes under normal conditions. Their richness and evenness are relatively stable in the retina compared to those in the RPE/choroid. Retinal laser injury enriches <i>Faecalibacterium</i> and <i>Bifidobacterium</i> in ocular tissues, and these microbiotas may participate in retinal wound healing through modulating inflammation.

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Publication Details

Journal
Frontiers in Ophthalmology
Published
2025-12-09
DOI
https://doi.org/10.3389/fopht.2025.1719090
Primary Topic
Ocular Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

The microbiome exists in the neuroretina and choroid in normal conditions and responds rapidly to retinal injury

Jian Liu, Xiang‐Ling Yuan, Caijiao Yi, Heping Xu et al.
Frontiers in Ophthalmology
Ocular Infections and Treatments
article

The microbiome exists in the neuroretina and choroid in normal conditions and responds rapidly to retinal injury

Jian Liu, Xiang‐Ling Yuan, Caijiao Yi, Heping Xu, Jinyan Qi, Xuexue Cui, Wen Deng
article en

Abstract

The neuroretina and RPE/choroid have diverse microbiomes under normal conditions. Their richness and evenness are relatively stable in the retina compared to those in the RPE/choroid. Retinal laser injury enriches <i>Faecalibacterium</i> and <i>Bifidobacterium</i> in ocular tissues, and these microbiotas may participate in retinal wound healing through modulating inflammation.

Frontiers in OphthalmologyVol. 5
Central South University (CN), He Eye Hospital (CN)
Openalex Percentile: Top 46%
Ocular Infections and Treatments
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