Functionalization of <i>N</i> -Aryl Tertiary Amines through Three-Component Reactions

A novel, mild approach featuring simplified operation has been developed for the direct synthesis of complex <i>N</i>-aryl tertiary amines via a three-component reaction, utilizing an electron donor-acceptor (EDA) complex strategy. In contrast to previous studies, which have primarily focused on two-component reaction systems for the functionalization of <i>N</i>-aryl tertiary amines, our method enables the functionalization of a diverse range of nitrogen-containing heterocyclic compounds and <i>N</i>,<i>N</i>-dialkylanilines under the established reaction conditions.