Genomic characterization of non-O1, non-O139 Vibrio cholerae causing rare clinical manifestation
This study represents the first investigation of a primary pulmonary Vibrio cholerae infection reported in Europe following a near-drowning event. While Vibrio vulnificus and Vibrio metschnikovii have been implicated in similar pneumonia cases, the precise virulence mechanisms of these species remain poorly understood. Although non-O1, non-O139 Vibrio cholerae infections associated with recreational water exposure are rare in Hungary (1-2 cases per year), this study underscores the importance of ongoing surveillance for the detection of potential outbreaks and to inform public health responses.
Authors
- Eszter Róka (ORCID: https://orcid.org/0009-0006-2919-0823)
- Eszter Mezei
- Ákos Tóth (ORCID: https://orcid.org/0000-0003-0048-567X)
- András Kállai
- Márta Vargha (ORCID: https://orcid.org/0000-0002-6426-2056)
- Szilárd Tóth (ORCID: https://orcid.org/0000-0003-1593-4984)
- Zoltán Kis (ORCID: https://orcid.org/0000-0002-6598-8369)
- Bernadett Khayer (ORCID: https://orcid.org/0000-0003-3484-9232)
- Judit Henczkó (ORCID: https://orcid.org/0009-0007-9195-8757)
- Bernadett Pályi (ORCID: https://orcid.org/0000-0003-1975-4198)
- Bereniké Novák (ORCID: https://orcid.org/0009-0004-0609-6610)
- Zsuzsanna Molnár
- Tünde Mag
- Koloman Krištof (ORCID: https://orcid.org/0000-0003-1573-4667)
Institutions
- Semmelweis University (HU)
- National Public Health and Medical Officer Service (HU)
- National Center for Epidemiology (HU)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1186/s12879-025-12191-9
- Primary Topic
- Vibrio bacteria research studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00