Dereplicative Combination of HPLC/DAD/MS and 2D NMR to Identify Lichexanthone Isomers in Lichen Extracts
In addition to HPLC/DAD/MS, NMR can be used directly on a lichen extract to confirm the positions of the chlorine atoms on the lichexanthone scaffold, thanks to the HSQC experiment. Furthermore, the NOESY experiment gives the position of methylations for a comprehensive overview of the substitution patterns involved in the extract of a xanthone-producing lichen, without requiring the entire series of the 64 derivatives.
Authors
- Marylène Chollet‐Krugler (ORCID: https://orcid.org/0000-0002-0457-0962)
- Françoise Lohézic‐Le Dévéhat (ORCID: https://orcid.org/0000-0003-4307-4942)
- Philippe Uriac (ORCID: https://orcid.org/0000-0002-2526-5967)
- Solenn Ferron (ORCID: https://orcid.org/0000-0002-3509-9982)
- Hermann Pinson
- Rania Marzoug
Institutions
- Centre National de la Recherche Scientifique (FR)
- Institut des Sciences Chimiques de Rennes (FR)
- Université de Rennes (FR)
Publication Details
- Journal
- Phytochemical Analysis
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1002/pca.70043
- Primary Topic
- Lichen and fungal ecology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Centre National de la Recherche Scientifique
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement