Silence of Transmembrane Channel-Like 5 Inhibits Cell Proliferation, Migration, and Invasion While Promoting Apoptosis Via Deactivating the AKT Pathway in Breast Cancer

The silence of TMC5 could inhibit the proliferation, migration, and invasion while promoting the apoptosis of breast cancer, while more in vivo validation is needed to explore its potential to be a treatment target for patients with breast cancer.

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Publication Details

Journal
Cancer Research and Treatment
Published
2025-12-09
DOI
https://doi.org/10.4143/crt.2025.805
Primary Topic
Ion channel regulation and function
Type
article
Field-Weighted Citation Impact
0.00
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article

Silence of Transmembrane Channel-Like 5 Inhibits Cell Proliferation, Migration, and Invasion While Promoting Apoptosis Via Deactivating the AKT Pathway in Breast Cancer

Jun Wan, Yang Li, Zhimin Liu
Cancer Research and Treatment
Ion channel regulation and function
article

Silence of Transmembrane Channel-Like 5 Inhibits Cell Proliferation, Migration, and Invasion While Promoting Apoptosis Via Deactivating the AKT Pathway in Breast Cancer

Jun Wan, Yang Li, Zhimin Liu
article en

Abstract

The silence of TMC5 could inhibit the proliferation, migration, and invasion while promoting the apoptosis of breast cancer, while more in vivo validation is needed to explore its potential to be a treatment target for patients with breast cancer.

Cancer Research and Treatment
Central Hospital of Wuhan (CN), Huazhong University of Science and Technology (CN)
Openalex Percentile: Top 65%
Ion channel regulation and function
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