Psychosine Alleviates Colitis via Inhibiting Th1 and Th17 Cell Immune Responses in Inflammatory Bowel Diseases
Our data reveal that psychosine reduces mucosal inflammation by preventing excessive Th1 and Th17 cell-mediated immune responses. Supplementation of psychosine may serve as a novel therapeutic approach for the treatment of IBD.
Authors
- Lan Zhong (ORCID: https://orcid.org/0000-0002-6947-3266)
- Jiayi Tu
- Qin-Juan Sun
- Ritian Lin (ORCID: https://orcid.org/0000-0003-3867-0061)
- Shan Li (ORCID: https://orcid.org/0000-0002-9995-989X)
Institutions
- Shanghai East Hospital (CN)
Publication Details
- Journal
- Journal of Gastroenterology and Hepatology
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1111/jgh.70199
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Shanghai Pudong New Area Health Commission