Detection of clinically relevant resistance genes in subgingival biofilms of chronic periodontitis: A cross-sectional molecular surveillance study

This pilot demonstrates a substantial prevalence and co-occurrence of resistance determinants in periodontal biofilms, underscoring the oral cavity's role in local and systemic AMR propagation. While preliminary, these findings support incorporating molecular resistance surveillance into periodontal diagnostics and tailoring region-specific antibiotic stewardship strategies to preserve therapeutic efficacy.

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Publication Details

Journal
Journal of Oral Biology and Craniofacial Research
Published
2025-12-09
DOI
https://doi.org/10.1016/j.jobcr.2025.12.002
Primary Topic
Oral microbiology and periodontitis research
Type
article
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article

Detection of clinically relevant resistance genes in subgingival biofilms of chronic periodontitis: A cross-sectional molecular surveillance study

Krishnasamy Nitya, Sameep Shetty, Aishwarya Arya, K Hema Shree
Journal of Oral Biology and Craniofacial Research
Oral microbiology and periodontitis research
article

Detection of clinically relevant resistance genes in subgingival biofilms of chronic periodontitis: A cross-sectional molecular surveillance study

Krishnasamy Nitya, Sameep Shetty, Aishwarya Arya, K Hema Shree
article en

Abstract

This pilot demonstrates a substantial prevalence and co-occurrence of resistance determinants in periodontal biofilms, underscoring the oral cavity's role in local and systemic AMR propagation. While preliminary, these findings support incorporating molecular resistance surveillance into periodontal diagnostics and tailoring region-specific antibiotic stewardship strategies to preserve therapeutic efficacy.

Journal of Oral Biology and Craniofacial ResearchVol. 16(1)
Saveetha University (IN)
Openalex Percentile: Top 54%
Oral microbiology and periodontitis research
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