Detection of clinically relevant resistance genes in subgingival biofilms of chronic periodontitis: A cross-sectional molecular surveillance study
This pilot demonstrates a substantial prevalence and co-occurrence of resistance determinants in periodontal biofilms, underscoring the oral cavity's role in local and systemic AMR propagation. While preliminary, these findings support incorporating molecular resistance surveillance into periodontal diagnostics and tailoring region-specific antibiotic stewardship strategies to preserve therapeutic efficacy.
Authors
- Krishnasamy Nitya (ORCID: https://orcid.org/0000-0001-6094-1206)
- Sameep Shetty (ORCID: https://orcid.org/0000-0001-8729-9348)
- Aishwarya Arya (ORCID: https://orcid.org/0000-0003-0626-4747)
- K Hema Shree
Institutions
- Saveetha University (IN)
Publication Details
- Journal
- Journal of Oral Biology and Craniofacial Research
- Published
- 2025-12-09
- DOI
- https://doi.org/10.1016/j.jobcr.2025.12.002
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00