Integrated peripheral metabolic and inflammatory biomarker signatures are associated with clinical deterioration in Creutzfeldt–Jakob disease
CJD involves coupled peripheral metabolic and inflammatory/proteolytic disturbances that may be associated with more severe brain degeneration and clinical decline, suggesting a possible multifaceted systemic component accompanying disease pathology.
Authors
- Hong Ye (ORCID: https://orcid.org/0000-0002-5345-1601)
- Zhongyun Chen (ORCID: https://orcid.org/0000-0001-6708-8391)
- Liyong Wu (ORCID: https://orcid.org/0000-0002-0684-6248)
- Miao Qu (ORCID: https://orcid.org/0000-0001-6289-9654)
- Chu Min
- Rui Liu (ORCID: https://orcid.org/0000-0002-9641-5280)
- Jing Zhang (ORCID: https://orcid.org/0000-0002-3082-8330)
- Yihao Wang (ORCID: https://orcid.org/0000-0003-1823-8335)
- Jia‐Hui Hou
Institutions
- Capital Medical University (CN)
Publication Details
- Journal
- Neurobiology of Disease
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1016/j.nbd.2025.107221
- Primary Topic
- Prion Diseases and Protein Misfolding
- Type
- article
- Field-Weighted Citation Impact
- 0.00