Flow Chemistry Processes for Drug Substance Synthesis: Applications Toward Pharmaceutical Production

Chemical synthesis in flow reactors (flow synthesis) has received significant research interest from both academia and industry. Flow synthesis offers several advantages over traditional synthesis in batch reactors. The most important features of flow synthesis include “precise mixing,” “precise temperature control,” and “precise residence time control.” Flash Chemistry is widely recognized as a representative example of flow synthesis, utilizing all three of these elements to achieve “chemical reaction control that cannot be realized with traditional batch synthesis.”