Visible-Light-Induced Difunctionalization of Alkenes with Thioacids and Quinoxalin-2(1 <i>H</i> )-ones
A visible-light-induced difunctionalization of alkenes with quinoxalin-2(1<i>H</i>)-ones and thioacids has been developed at room temperature. The present protocol, which utilizes 4CzIPN as the photocatalyst and K<sub>3</sub>PO<sub>4</sub> as base, provides a series of structurally diverse thioester-containing quinoxalin-2(1<i>H</i>)-ones in moderate to good yields. This transformation undergoes through a radical pathway with the simultaneous installation of thioester and quinoxalin-2(1<i>H</i>)-one into one structural framework.
Authors
- Huilan Yue (ORCID: https://orcid.org/0000-0003-4457-3233)
- Zhen Ma (ORCID: https://orcid.org/0000-0002-2391-4943)
- Zi Yang (ORCID: https://orcid.org/0000-0002-8377-118X)
- Huanhuan Cui (ORCID: https://orcid.org/0000-0002-6190-6135)
- Dong Yi (ORCID: https://orcid.org/0000-0002-8281-7860)
- Wei Wei (ORCID: https://orcid.org/0000-0002-0015-7636)
- Hua Xia (ORCID: https://orcid.org/0000-0003-0923-6493)
- Zuli Wang (ORCID: https://orcid.org/0009-0003-2695-8743)
Institutions
- Changsha Medical University (CN)
- Nanjing Forestry University (CN)
- Southwest Medical University (CN)
- Qinghai Tibetan Hospital (CN)
- Green Chemistry (PL)
- Zaozhuang University (CN)
- Northwest Institute of Plateau Biology
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1021/acs.joc.5c02640
- Citations
- 4
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 3.74