Comparison of Activation Techniques for the Identification of Nitazene Analogs Using the NIST/NIJ Data Interpretation Tool
All three activation techniques performed similarly, based on the NIST/NIJ DIT results. However, IS-CID produced significantly less fragmentation than CID or AIF, indicating that AIF is a suitable screening technique for this instrumental setup. The NIST/NIJ DIT can also be utilized for ESI-CID spectra, although slightly fewer nitazene analogs were correctly identified with ESI-CID than with DART-CID.
Authors
- Alleigh N. Couch (ORCID: https://orcid.org/0000-0003-4528-3561)
- J. Tyler Davidson (ORCID: https://orcid.org/0000-0001-9932-8273)
- Emma K. Hardwick
Institutions
- Sam Houston State University (US)
Publication Details
- Journal
- Rapid Communications in Mass Spectrometry
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1002/rcm.70004
- Primary Topic
- Chemical Reactions and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00