Heart rate changes in chronically red cell transfusion‐dependent patients—A dose‐dependent effect of red cell transfusion: A randomized cross‐over trial, interim analysis
This interim analysis suggests that higher post-transfusion hemoglobin is associated with lower heart rate, reflecting enhanced oxygen delivery. Wearable monitoring was sensitive to these changes. Nonsignificant, hypothesis-generating trends toward improved QoL, fatigue, and cognition were observed.
Authors
- Lizan Hardi
- Rik Paulus Bernardus Tonino (ORCID: https://orcid.org/0000-0002-6775-6617)
- Jaap Jan Zwaginga (ORCID: https://orcid.org/0000-0003-1228-7769)
- Martin R. Schipperus
- Nicolette Leonie Tiren-Verbeet
- Rolf E. Brouwer (ORCID: https://orcid.org/0009-0001-5661-3290)
Institutions
- Leiden University Medical Center (NL)
- Sanquin (NL)
- Reinier de Graaf Hospital (NL)
- National Blood Transfusion Service (NG)
- Alrijne Ziekenhuis (NL)
- Groene Hart Ziekenhuis (NL)
Publication Details
- Journal
- Transfusion
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1111/trf.70023
- Primary Topic
- Blood transfusion and management
- Type
- article
- Field-Weighted Citation Impact
- 0.00