Cardiac 3D Motion Reconstruction Using Dual-Camera Defocused Speckle Imaging With Multi-Scale Amplification

Cardiovascular diseases are one of the leading causes of death worldwide. Accurately capturing and analyzing the multidimensional dynamics of cardiac motion is crucial for early diagnosis and rehabilitation assessment. This study introduces a novel concept for non-contact cardiac linear vibration (SCG) and rotational components (GCGx and GCGy) decoupling and reconstruction by integrating speckle motion signals captured from two cameras with different defocus levels. The intention is to overcome the motion coupling issues inherent in single-camera imaging and improve the accuracy in characterizing the cardiac complex 3D mechanical behavior. Using a sternum-mounted inertial sensor as the reference, experiments were conducted on 42 subjects in laboratory and intensive care unit settings. The results show that the reconstructed cardiac 3D motion signals exhibit greater waveform similarity to the reference signal than the raw speckle motion signal from a single camera, with similarity indices above 87.471%. In addition, with an 8 ms tolerance error, the localization accuracy of 6 key biomarkers (aortic valve opening/closing (AO/AC), mitral valve opening/closing (MO/MC), the biomarkers corresponding to the AO event in GCGy and the MC event in GCGx) are 73.080%, 99.998%, 85.587%, 86.617%, 99.683% and 77.301%, respectively. These results also outperform those obtained from the raw speckle motion signal. These findings validate the rationale and effectiveness of using dual-camera imaging with different defocus levels to reconstruct SCG, GCGx, and GCGy, offering a promising approach for accurately capturing complex cardiac 3D motion and improving cardiac function assessment.