A Case Report of Endometrioid Carcinoma of the Ovary: A Comprehensive Clinical, Pathological, and Molecular Perspective

Endometrioid carcinoma (EC) of the ovary represents a distinct subtype of epithelial ovarian cancers, comprising approximately 10%-20% of all ovarian malignancies. It is histologically similar to endometrial carcinoma of the uterus and is often associated with endometriosis. This article presents a comprehensive case report of a 64-year-old postmenopausal woman diagnosed with stage pT1aNxM0 EC of the ovary. We detail her clinical presentation, radiological and histopathological findings, surgical management, and molecular implications. Through an extensive literature review and analysis, this paper aims to emphasize the significance of early detection, the histological diversity of EC, its differential diagnosis, and current perspectives on its molecular pathogenesis and targeted therapies.

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Journal
Journal of Mid-life Health
Published
2025-10-01
DOI
https://doi.org/10.4103/jmh.jmh_150_25
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
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article

A Case Report of Endometrioid Carcinoma of the Ovary: A Comprehensive Clinical, Pathological, and Molecular Perspective

S Swetha, Nabnita Patnaik, Gunvanti Rathod, Monica Mishra et al.
Journal of Mid-life Health
Ovarian cancer diagnosis and treatment
article

A Case Report of Endometrioid Carcinoma of the Ovary: A Comprehensive Clinical, Pathological, and Molecular Perspective

S Swetha, Nabnita Patnaik, Gunvanti Rathod, Monica Mishra, K Aslam
article en

Abstract

Endometrioid carcinoma (EC) of the ovary represents a distinct subtype of epithelial ovarian cancers, comprising approximately 10%-20% of all ovarian malignancies. It is histologically similar to endometrial carcinoma of the uterus and is often associated with endometriosis. This article presents a comprehensive case report of a 64-year-old postmenopausal woman diagnosed with stage pT1aNxM0 EC of the ovary. We detail her clinical presentation, radiological and histopathological findings, surgical management, and molecular implications. Through an extensive literature review and analysis, this paper aims to emphasize the significance of early detection, the histological diversity of EC, its differential diagnosis, and current perspectives on its molecular pathogenesis and targeted therapies.

Journal of Mid-life HealthVol. 16(4)
All India Institute of Medical Sciences Bhopal (IN), All India Institute of Medical Sciences (IN)
Openalex Percentile: Top 50%
Ovarian cancer diagnosis and treatment
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A Case Report of Endometrioid Carcinoma of the Ovary: A Comprehensive Clinical, Pathological, and Molecular Perspective — S Swetha, Nabnita Patnaik, et al. · Journal of Mid-life Health (2025) | TGRS Research Map | TGRS