Correlation of meconium-stained amniotic fluid with subclinical chorioamnionitis and associated cardiotocographic changes

Our study aims to correlate meconium-stained amniotic fluid with subclinical chorio-amnionitis and associated cardio-tocographic (CTG) changes in women of >34 week gestation. We found CTG abnormalities in 47.2% cases and 24.1% controls, showing a significant correlation between meconium stained amniotic fluid and CTG abnormalities. These were not significantly associated with subclinical chorio-amnionitis, though the neonatal outcome of these babies was worse. Consequently, it is essential to balance the use of CTG with clinical judgement and other diagnostic tools to avoid unnecessary Caesarean section, while ensuring the safety of both mother and foetus.

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Publication Details

Journal
Tropical Doctor
Published
2025-12-08
DOI
https://doi.org/10.1177/00494755251404851
Primary Topic
Neonatal Respiratory Health Research
Type
article
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article

Correlation of meconium-stained amniotic fluid with subclinical chorioamnionitis and associated cardiotocographic changes

Aruna Nigam, Dina Aisha Khan, Tanya Grover, Nidhi Gupta et al.
Tropical Doctor
Neonatal Respiratory Health Research
article

Correlation of meconium-stained amniotic fluid with subclinical chorioamnionitis and associated cardiotocographic changes

Aruna Nigam, Dina Aisha Khan, Tanya Grover, Nidhi Gupta, Sumedha Sharma
article en

Abstract

Our study aims to correlate meconium-stained amniotic fluid with subclinical chorio-amnionitis and associated cardio-tocographic (CTG) changes in women of >34 week gestation. We found CTG abnormalities in 47.2% cases and 24.1% controls, showing a significant correlation between meconium stained amniotic fluid and CTG abnormalities. These were not significantly associated with subclinical chorio-amnionitis, though the neonatal outcome of these babies was worse. Consequently, it is essential to balance the use of CTG with clinical judgement and other diagnostic tools to avoid unnecessary Caesarean section, while ensuring the safety of both mother and foetus.

Tropical DoctorVol. 56(2)
Hamdard University (PK)
Openalex Percentile: Top 42%
Neonatal Respiratory Health Research
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Correlation of meconium-stained amniotic fluid with subclinical chorioamnionitis and associated cardiotocographic changes — Aruna Nigam, Dina Aisha Khan, et al. · Tropical Doctor (2025) | TGRS Research Map | TGRS