Modern understanding of epigenetic inheritance mechanisms and their role in the evolutionary process
This review summarizes current advances in the study of epigenetic inheritance and its integration into evolutionary theory. It discusses modern methods for studying epigenetic mechanisms of inheritance, including the use of next-generation high-throughput sequencing to analyze DNA methylation and histone modifications. It describes the contribution of epigenetic variability to evolutionary processes, transgenerational epigenetic inheritance involving the transmission of DNA methylation, post-translational histone modifications, and non-coding RNAs. In addition, the review touches on the adaptive significance of epigenetic inheritance mechanisms.
Authors
- Stepan V. Toshchakov (ORCID: https://orcid.org/0000-0001-7549-3450)
- Sergey Noskov (ORCID: https://orcid.org/0009-0006-1578-1382)
- T.V. Erofeeva (ORCID: https://orcid.org/0009-0003-6896-6821)
- V.A. Toshchakova
- K.R. Khazieva (ORCID: https://orcid.org/0009-0008-5290-6484)
Institutions
- Kurchatov Institute (RU)
- Research Centre for Medical Genetics (RU)
- All-Russian Scientific Research Institute of Food Biotechnology (RU)
Publication Details
- Journal
- Molecular Genetics Microbiology and Virology (Russian)
- Published
- 2025-12-08
- DOI
- https://doi.org/10.17116/molgen2025430426
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00