Left Atrial Appendage Closure Versus Oral Anticoagulants in Atrial Fibrillation: A Systematic Review and Meta-Analysis
In AF patients, LAA closure significantly reduces mortality and a composite clinical endpoint compared to OAC, with similar risks of stroke and major bleeding. It is a favorable alternative for patients unsuitable for long-term anticoagulation.
Authors
- Dan Zhu (ORCID: https://orcid.org/0000-0002-3640-4758)
- Jinliang Nan (ORCID: https://orcid.org/0000-0003-0986-7877)
- Chen Wang (ORCID: https://orcid.org/0000-0003-2638-3081)
- Danyang Zhang (ORCID: https://orcid.org/0009-0004-8288-3501)
Institutions
- Blood Center of Zhejiang Province (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
Publication Details
- Journal
- Journal of Cardiovascular Development and Disease
- Published
- 2025-12-08
- DOI
- https://doi.org/10.3390/jcdd12120483
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00