Therapeutic Potentials of Phytochemicals in Pancreatitis: Targeting Calcium Signaling, Ferroptosis, microRNAs, and Inflammation with Drug-Likeness Evaluation
Phytochemicals represent a promising reservoir of multitarget therapeutic agents for pancreatitis. Their ability to modulate oxidative stress, inflammatory and calcium signaling, ferroptosis, and microRNA networks highlights their translational potential. Future studies should focus on clinical validation, bioavailability optimization, and advanced delivery platforms to bridge the gap from bench to bedside.
Authors
- Shreesh Ojha (ORCID: https://orcid.org/0000-0001-7801-2966)
- Sandeep B. Subramanya (ORCID: https://orcid.org/0000-0002-4802-500X)
- Bhoomendra A. Bhongade (ORCID: https://orcid.org/0000-0002-4057-7125)
- Mauro Pessia (ORCID: https://orcid.org/0000-0002-2857-6795)
- Balaji Venkataraman (ORCID: https://orcid.org/0000-0001-6561-2399)
- Fatma Farhat (ORCID: https://orcid.org/0000-0003-0289-8216)
Institutions
- United Arab Emirates University (AE)
- Helwan University (EG)
- Ras al-Khaimah Medical and Health Sciences University (AE)
Publication Details
- Journal
- Nutrients
- Published
- 2025-12-08
- DOI
- https://doi.org/10.3390/nu17243841
- Citations
- 1
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- United Arab Emirates University