Urological management in a pediatric patient with mixed gonadal dysgenesis
Disorders of sex development are conditions characterized by alterations in gonadal development that lead to discordance between chromosomal sex, gonadal sex, and phenotypic sex. We report the case of a 4 years old patient with ambiguous genitalia and 45,X/46,XY karyotype. A rudimentary uterus was visualized, and bilateral inguinal exploration was performed, during which the residual right spermatic cord was ligated and orchiectomy of the left testis located in the inguinal canal was carried out. This case highlights the relevance of clinical findings identified during physical examination and emphasizes the importance of multidisciplinary management due to the risk of gonadal malignancy.
Authors
- Francisco Miguel Izquierdo (ORCID: https://orcid.org/0000-0003-1285-3601)
- Vanessa Vega Córdova (ORCID: https://orcid.org/0000-0003-3333-4798)
- Wilmer Silva-Caso (ORCID: https://orcid.org/0000-0003-1086-8084)
- Ronald Aquino-Ortega (ORCID: https://orcid.org/0000-0002-9100-8547)
- Juana del Valle-Mendoza (ORCID: https://orcid.org/0000-0002-6011-5040)
- Wendy Matilde Chipa Beizaga
- Luis José Orbegoso Celis
- Brandon Juced Torres Marigorda
- Miguel Martín Aguilar Ulloque
- Kilder Nicolay García Murga
Institutions
- Peruvian University of Applied Sciences (PE)
- Hospital Nacional Dos de Mayo (PE)
- Hospital Base Guillermo Almenara Irigoyen (PE)
- St Martins Hospital (GB)
Publication Details
- Journal
- Urology Case Reports
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1016/j.eucr.2025.103311
- Primary Topic
- Sexual Differentiation and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00