Comparing content within a culturally-adapted digital treatment for Hispanic patients with alcohol use disorder

Hispanic people in the U.S. experience alcohol-related harms comparable to non-Hispanic White people. Hispanic people often face more challenges to accessing alcohol use disorder (AUD) treatment. Culturally-adapted digital therapeutics may improve treatment access. Using data from two clinical trials of a culturally-adapted digital cognitive behavioral therapy program for Spanish-speaking Hispanic people (CBT4CBT-S, n = 43), we identified which program topics were most strongly linked to outcomes (NCT03474588 registered on 3/15/2018 and NCT02043210 registered on 1/10/2014 at clinicaltrials.gov). Topics were not administered in a randomized order. Participants drank less alcohol after completing content about coping with craving (OR = 0.48), cognitive restructuring (OR = 0.73), and problem solving (OR = 0.79). Participants were slightly more favorable towards content about cognitive restructuring (b = 0.14) and decision making (b = 0.09). These findings can inform further development of culturally-adapted digital therapeutics for AUD, which may improve alcohol-related health outcomes for Hispanic people.

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Journal
npj Digital Medicine
Published
2025-12-08
DOI
https://doi.org/10.1038/s41746-025-02197-7
Primary Topic
Substance Abuse Treatment and Outcomes
Type
article
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article

Comparing content within a culturally-adapted digital treatment for Hispanic patients with alcohol use disorder

Brian D. Kiluk, Charla Nich, Bryan Benitez, Tami Frankforter et al.
npj Digital Medicine
Substance Abuse Treatment and Outcomes
article

Comparing content within a culturally-adapted digital treatment for Hispanic patients with alcohol use disorder

Brian D. Kiluk, Charla Nich, Bryan Benitez, Tami Frankforter, Manuel Paris
article en

Abstract

Hispanic people in the U.S. experience alcohol-related harms comparable to non-Hispanic White people. Hispanic people often face more challenges to accessing alcohol use disorder (AUD) treatment. Culturally-adapted digital therapeutics may improve treatment access. Using data from two clinical trials of a culturally-adapted digital cognitive behavioral therapy program for Spanish-speaking Hispanic people (CBT4CBT-S, n = 43), we identified which program topics were most strongly linked to outcomes (NCT03474588 registered on 3/15/2018 and NCT02043210 registered on 1/10/2014 at clinicaltrials.gov). Topics were not administered in a randomized order. Participants drank less alcohol after completing content about coping with craving (OR = 0.48), cognitive restructuring (OR = 0.73), and problem solving (OR = 0.79). Participants were slightly more favorable towards content about cognitive restructuring (b = 0.14) and decision making (b = 0.09). These findings can inform further development of culturally-adapted digital therapeutics for AUD, which may improve alcohol-related health outcomes for Hispanic people.

npj Digital MedicineVol. 9(1)
Yale University (US)
Openalex Percentile: Top 50%
Substance Abuse Treatment and Outcomes
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Comparing content within a culturally-adapted digital treatment for Hispanic patients with alcohol use disorder — Brian D. Kiluk, Charla Nich, et al. · npj Digital Medicine (2025) | TGRS Research Map | TGRS