Co-use of opioids and cannabis versus single-substance use: a national analysis of US adults

Individuals who use opioids only, cannabis only, or both substances differ significantly across demographic, socioeconomic, and health-related factors. These distinctions highlight the need for tailored clinical guidance and public health responses that account for co-use patterns and geographic context to support safer pain management and substance use care.

Authors

Jiajun Tian
Gary Milavetz (ORCID: https://orcid.org/0000-0002-3822-1285)
Hyojung Kang (ORCID: https://orcid.org/0000-0001-7429-1101)

Institutions

University of Iowa (US)
University of Illinois Urbana-Champaign (US)
Duke University (US)

Publication Details

Journal: Frontiers in Public Health
Published: 2025-12-08
DOI: https://doi.org/10.3389/fpubh.2025.1623420
Primary Topic: Opioid Use Disorder Treatment
Type: article
Field-Weighted Citation Impact: 0.00

Funders

University of Illinois at Urbana-Champaign
Center on Health, Aging, and Disability

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article

Co-use of opioids and cannabis versus single-substance use: a national analysis of US adults

Jiajun Tian, Gary Milavetz, Hyojung Kang

Dec 8, 2025

Frontiers in Public Health

Opioid Use Disorder Treatment

article

Co-use of opioids and cannabis versus single-substance use: a national analysis of US adults

Jiajun Tian, Gary Milavetz, Hyojung Kang

December 8, 2025article en

Abstract

Individuals who use opioids only, cannabis only, or both substances differ significantly across demographic, socioeconomic, and health-related factors. These distinctions highlight the need for tailored clinical guidance and public health responses that account for co-use patterns and geographic context to support safer pain management and substance use care.

Frontiers in Public HealthVol. 13

University of Iowa (US), University of Illinois Urbana-Champaign (US), Duke University (US)

University of Illinois at Urbana-Champaign, Center on Health, Aging, and Disability

Openalex Percentile: Top 50%

Opioid Use Disorder Treatment

DOI Open Access PDF OpenAlex

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Co-use of opioids and cannabis versus single-substance use: a national analysis of US adults — Jiajun Tian, Gary Milavetz, et al. · Frontiers in Public Health (2025) | TGRS Research Map | TGRS