Antiproliferative and apoptotic activity of a Zn(II) complex against cancer cells, both in vitro and in vivo
The [Zn(L<sub>CX</sub>)(NCS)₂] complex demonstrated potent anticancer activity, followed by induction of apoptosis with minor host toxicity, positioning it as a viable option for advancement as an efficient chemotherapeutic agent. However, more research and clinical studies with animal and human models are needed to further develop the compound as a chemotherapeutic agent.
Authors
- Nitai Roy (ORCID: https://orcid.org/0000-0002-8454-6128)
- Farhadul Islam (ORCID: https://orcid.org/0000-0001-5262-4702)
- Syed Rashel Kabir (ORCID: https://orcid.org/0000-0002-5708-014X)
- Tapashi G. Roy (ORCID: https://orcid.org/0000-0002-2192-1584)
- M. Habibur Rahman (ORCID: https://orcid.org/0000-0001-9841-4903)
- Tumpa Rani Majumder
- Saswata Rabi (ORCID: https://orcid.org/0000-0001-5911-1184)
- Kazi Soha
- Md Arifur Rahman (ORCID: https://orcid.org/0000-0002-5616-1650)
- Tasfik Ul Haque Pronoy
- Abdul Auwal
- K M Rashel
- MA Hossain
- Jahan Ara Khanam
- Pradip C. Paul (ORCID: https://orcid.org/0009-0000-7436-6038)
- Tasnima Kamal
Institutions
- Chittagong University of Engineering & Technology (BD)
- Patuakhali Science and Technology University (BD)
- University of Chittagong (BD)
- University of Rajshahi (BD)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1007/s12672-025-04214-3
- Primary Topic
- Metal complexes synthesis and properties
- Type
- article
- Field-Weighted Citation Impact
- 0.00