Evaluation of sex differences in survival among glioblastoma patients treated with immune checkpoint inhibitors
In nGBM and rGBM, ICI therapy was not associated with sex difference in PFS or OS. Clinically meaningful sex-based outcome differences may be better understood by prospective evaluation in clinical trials.
Authors
- Brooke Barlow (ORCID: https://orcid.org/0000-0001-5118-7029)
- L. Nicolas Gonzalez Castro (ORCID: https://orcid.org/0000-0001-7699-5188)
- Loai J. A. Aker (ORCID: https://orcid.org/0000-0001-6344-0984)
- Tamar R. Berger
- Alona Muzikansky (ORCID: https://orcid.org/0000-0001-7585-8181)
- John Yohan Rhee (ORCID: https://orcid.org/0000-0002-2081-5667)
- Lakshmi Nayak (ORCID: https://orcid.org/0000-0003-2725-8717)
- Patrick Yung Wen (ORCID: https://orcid.org/0000-0002-0774-7700)
- Gilbert Youssef (ORCID: https://orcid.org/0000-0001-6109-7692)
- Aleksandra B Lasica (ORCID: https://orcid.org/0000-0002-9739-5103)
- Thomas Nelson (ORCID: https://orcid.org/0000-0003-3942-5527)
- J Ricardo McFaline-Figueroa (ORCID: https://orcid.org/0000-0002-6670-1841)
- Zhou Lan
- Eudocia Q. Lee (ORCID: https://orcid.org/0000-0003-3355-5179)
- Vihang Nakhate (ORCID: https://orcid.org/0000-0002-2941-9740)
- Elisa Aquilanti (ORCID: https://orcid.org/0000-0002-1343-5017)
- Rameen Beroukhim (ORCID: https://orcid.org/0000-0001-6303-3609)
- Ian Pan (ORCID: https://orcid.org/0000-0002-0650-6614)
- Ugonma Nnenna Chukwueke (ORCID: https://orcid.org/0000-0003-0598-9535)
- Alyssa Russ (ORCID: https://orcid.org/0000-0002-6353-139X)
- David A. Reardon (ORCID: https://orcid.org/0000-0001-6674-0157)
- Chibueze D. Nwagwu
- Raymond Y. Huang (ORCID: https://orcid.org/0000-0001-7661-797X)
- Tracy T. Batchelor (ORCID: https://orcid.org/0000-0001-7568-6607)
- Albert Jiao (ORCID: https://orcid.org/0000-0003-3354-1850)
- Catharina Westergaard
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- University of California, San Francisco (US)
- NYU Langone Health (US)
- Massachusetts General Hospital (US)
- Center for Neuro-Oncology (US)
- Dana-Farber Cancer Institute (US)
- New York University (US)
Publication Details
- Journal
- Neuro-Oncology Advances
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1093/noajnl/vdaf250
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00