It is time to have a molecular test for diagnosing <i>Kingella kingae</i> infections in the lab!

The article by S. J. Oyeniran, A. L. Leber and H. Wang (J Clin Microbiol 63:e00986-25, 2025, https://doi.org/10.1128/jcm.00986-25) describes a novel laboratory-developed diagnostic PCR assay that amplifies the gene encoding <i>Kingella kingae</i>'s major outer membrane protein. The test confirmed the prime role of the organism causing skeletal system infections in preschoolers and enabled the administration of targeted antibiotic therapy. It is hoped that a much-needed commercial <i>K. kingae</i>-specific molecular test will soon receive FDA clearance to improve the management of pediatric osteoarticular infections.

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Publication Details

Journal
Journal of Clinical Microbiology
Published
2025-12-08
DOI
https://doi.org/10.1128/jcm.01532-25
Primary Topic
Orthopedic Infections and Treatments
Type
article
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article

It is time to have a molecular test for diagnosing Kingella kingae infections in the lab!

Pablo Yagupsky
Journal of Clinical Microbiology
Orthopedic Infections and Treatments
article

It is time to have a molecular test for diagnosing Kingella kingae infections in the lab!

Pablo Yagupsky
article en

Abstract

The article by S. J. Oyeniran, A. L. Leber and H. Wang (J Clin Microbiol 63:e00986-25, 2025, https://doi.org/10.1128/jcm.00986-25) describes a novel laboratory-developed diagnostic PCR assay that amplifies the gene encoding <i>Kingella kingae</i>'s major outer membrane protein. The test confirmed the prime role of the organism causing skeletal system infections in preschoolers and enabled the administration of targeted antibiotic therapy. It is hoped that a much-needed commercial <i>K. kingae</i>-specific molecular test will soon receive FDA clearance to improve the management of pediatric osteoarticular infections.

Journal of Clinical MicrobiologyVol. 64(2)
Ben-Gurion University of the Negev (IL)
Openalex Percentile: Top 42%
Orthopedic Infections and Treatments
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