First exposure to second-generation antipsychotics alters gut microbiota and metabolic profiles in patients with glucose-lipid metabolism disorders
In summary, first-time exposure to second-generation antipsychotics in patients with schizophrenia is associated with disturbances in glucose and lipid metabolism, which appear to be closely linked to SGA-induced perturbations in gut microbiota composition and their associated metabolic profiles.
Authors
- Jingsong Huang (ORCID: https://orcid.org/0000-0001-7730-3518)
- Zhiming Wu (ORCID: https://orcid.org/0000-0002-1468-5763)
- Yuexia Wu (ORCID: https://orcid.org/0000-0003-2788-6545)
- Shusheng Zang
Institutions
- Dalian Medical University (CN)
- Xi’an Children’s Hospital (CN)
- Seventh People's Hospital of Dalian (CN)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2025-12-08
- DOI
- https://doi.org/10.3389/fpsyt.2025.1722760
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00