Quantitative computed tomography for assessing body composition in schizophrenia: a potential indicator of insulin resistance
Visceral adipose tissue and liver fat content, as measured by QCT, are robust and independent indicator of insulin resistance in patients with schizophrenia. A model combining QCT parameters with basic clinical covariates offers the best predictive performance for identifying IR risk in this population, highlighting the critical role of ectopic fat deposition in metabolic dysregulation.
Authors
- Mengyang Han
- Fangsong Zhang (ORCID: https://orcid.org/0000-0002-2089-2806)
- Chanjun Ding
- Yuan Qin (ORCID: https://orcid.org/0000-0001-5389-7227)
- Lili Yuan (ORCID: https://orcid.org/0000-0002-5497-6338)
- Xuexue Wang
- Xinping Kuai
- Jianye Zhang (ORCID: https://orcid.org/0000-0002-9579-1399)
- Lei Chen (ORCID: https://orcid.org/0000-0001-5596-127X)
- Jinhong Wang (ORCID: https://orcid.org/0000-0002-7552-5771)
- Z. Xu (ORCID: https://orcid.org/0000-0001-8634-520X)
Institutions
- Shanghai Mental Health Center (CN)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2025-12-08
- DOI
- https://doi.org/10.3389/fpsyt.2025.1676939
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- China Postdoctoral Science Foundation