Effect of Prophylactic Administration of Foscarnet for HHV‐6 Encephalitis in Adult Single Cord Blood Transplantation

Foscarnet prophylaxis was not significantly associated with a reduced incidence of HHV-6 encephalitis after UCBT, whereas high-dose steroid exposure was a risk factor. Notably, a lower incidence of encephalitis with foscarnet prophylaxis was observed in the low-dose steroid subgroup, although this finding requires confirmation in larger cohorts.

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Publication Details

Journal
Transplant Infectious Disease
Published
2025-12-08
DOI
https://doi.org/10.1111/tid.70147
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
0.00
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article

Effect of Prophylactic Administration of Foscarnet for HHV‐6 Encephalitis in Adult Single Cord Blood Transplantation

Kouhei Yamashita, Tomoki Iemura, Akifumi Takaori‐Kondo, Chisaki Mizumoto et al.
Transplant Infectious Disease
Cytomegalovirus and herpesvirus research
article

Effect of Prophylactic Administration of Foscarnet for HHV‐6 Encephalitis in Adult Single Cord Blood Transplantation

Kouhei Yamashita, Tomoki Iemura, Akifumi Takaori‐Kondo, Chisaki Mizumoto, Junya Kanda, Yutaka Shimazu, Kotaro Suzuki, Yasuyuki Arai, Toshio Heike
article en

Abstract

Foscarnet prophylaxis was not significantly associated with a reduced incidence of HHV-6 encephalitis after UCBT, whereas high-dose steroid exposure was a risk factor. Notably, a lower incidence of encephalitis with foscarnet prophylaxis was observed in the low-dose steroid subgroup, although this finding requires confirmation in larger cohorts.

Transplant Infectious DiseaseVol. 28(1)
Kyoto University (JP), Kyoto University Hospital (JP)
Openalex Percentile: Top 50%
Cytomegalovirus and herpesvirus research
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