Achilles tendons of MRL/MpJ mice show scar-mediated healing after tenotomy
These findings indicate that MRL/MpJ mice possess limited capacity to regenerate injured tendons after complete rupture, and that tenotomized Achilles tendons of MRL/MpJ male mice have lesser induction of heterotopic ossification and lower activation of the signaling pathways also induced with injury in C57BL/6J male mice.
Authors
- Catherine K. Kuo (ORCID: https://orcid.org/0000-0002-8274-418X)
- Christoph Hart
- James A. Glazier (ORCID: https://orcid.org/0000-0003-3634-190X)
- Hongying Tian
- Kimberly Wilson (ORCID: https://orcid.org/0000-0002-2923-2708)
- Tao L. Lowe (ORCID: https://orcid.org/0000-0003-2882-0409)
- Natalie L. Leong (ORCID: https://orcid.org/0000-0001-6556-9781)
- Maureen A. Kane (ORCID: https://orcid.org/0000-0002-5525-9170)
- Jie Jiang (ORCID: https://orcid.org/0000-0001-6619-1936)
- Motomi Enomoto‐Iwamoto (ORCID: https://orcid.org/0000-0002-1898-5974)
- Masahiro Iwamoto
- Ningfeng Tang
- Divya S. Sivalingam
Institutions
- University of Maryland, Baltimore (US)
- University of Maryland, College Park (US)
Publication Details
- Journal
- Connective Tissue Research
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1080/03008207.2025.2594694
- Primary Topic
- Tendon Structure and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00