Proteomic and Transcriptomic Signatures of Poor Asthma Symptom Control in the U‐BIOPRED Cohort
Four serum proteins distinguished asthmatics with uncontrolled from controlled symptoms. CD5L levels were also lower in asthmatics with severe disease than in healthy controls, warranting further investigation into its potential therapeutic value.
Authors
- L. Andersson (ORCID: https://orcid.org/0000-0002-5257-4052)
- Sven‐Erik Dahlén (ORCID: https://orcid.org/0000-0002-4993-4002)
- Frits M.E. Franssen (ORCID: https://orcid.org/0000-0002-1633-6356)
- Paolo Montuschi (ORCID: https://orcid.org/0000-0001-5589-1750)
- Martijn A. Spruit (ORCID: https://orcid.org/0000-0003-3822-7430)
- Alda Sofia Pires De Dias Marques (ORCID: https://orcid.org/0000-0003-4980-6200)
- Nazanin Zounemat Kermani (ORCID: https://orcid.org/0000-0003-2479-3861)
- Ian Michael Adcock (ORCID: https://orcid.org/0000-0003-2101-8843)
- Joana Antão (ORCID: https://orcid.org/0000-0002-2251-4833)
- Qichen Deng (ORCID: https://orcid.org/0000-0003-3835-9142)
- Scott Wagers
- Guilherme Rodrigues (ORCID: https://orcid.org/0000-0002-1483-6912)
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Karolinska University Hospital (SE)
- Maastricht University Medical Centre (NL)
- Karolinska Institutet (SE)
- Maastricht University (NL)
- BioSciCon (United States) (US)
- NIHR Imperial Biomedical Research Centre (GB)
- Ciro (NL)
- University of the Sacred Heart (JP)
- Imperial College London (GB)
- University of Aveiro (PT)
Publication Details
- Journal
- Allergy
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1111/all.70178
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Amgen
- Bristol-Myers Squibb
- Pulmonary Fibrosis Foundation
- AstraZeneca
- GlaxoSmithKline
- Sanofi
- Teva Pharmaceutical Industries
- Chiesi Farmaceutici
- Aix-Marseille Université
- Universidade de Aveiro
- Uniwersytet Jagielloński Collegium Medicum
- University of Bern
- Sunovion
- Wellcome Trust
- Royal Brompton and Harefield NHS Foundation Trust
- European Federation of Pharmaceutical Industries and Associations
- Inselspital, Universitätsspital Bern
- Amsterdam University Medical Centers
- National Institute for Health and Care Research
- Asthma and Lung UK
- University of Southampton
- Imperial College London
- Institut National de la Santé et de la Recherche Médicale
- Universiteit van Amsterdam
- Semmelweis Egyetem
- Gentofte Hospital
- Università Campus Bio-Medico di Roma
- Karolinska Institutet
- Kungliga Tekniska Högskolan
- Stichting Astma Bestrijding
- Università di Catania
- Centre National de la Recherche Scientifique
- Umeå Universitet
- Universitetet i Bergen
- Università Cattolica del Sacro Cuore
- Université Claude Bernard Lyon 1
- Uppsala Universitet
- Science for Life Laboratory
- Université de Lyon
- Directorate for Biological Sciences
- Novartis Institutes for BioMedical Research
- Fundação para a Ciência e a Tecnologia