Investigation of Tight Junction Protein Alterations in ADHD: The Role of Claudin-5, β-Catenin and Paxillin

This study suggests that claudin-5 and beta-catenin may play a role in the pathogenesis of ADHD. These proteins may affect the brain by causing a dysregulation in BBB permeability or through other mechanisms.

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Publication Details

Journal
Journal of Attention Disorders
Published
2025-12-08
DOI
https://doi.org/10.1177/10870547251400398
Primary Topic
Barrier Structure and Function Studies
Type
article
Field-Weighted Citation Impact
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article

Investigation of Tight Junction Protein Alterations in ADHD: The Role of Claudin-5, β-Catenin and Paxillin

Ahmet Osman Kılıç, Ayhan Bi̇lgi̇ç, Necati Uzun, Mehmet Berat Taş et al.
Journal of Attention Disorders
Barrier Structure and Function Studies
article

Investigation of Tight Junction Protein Alterations in ADHD: The Role of Claudin-5, β-Catenin and Paxillin

Ahmet Osman Kılıç, Ayhan Bi̇lgi̇ç, Necati Uzun, Mehmet Berat Taş, İbrahim Kılınç, Hurşit Ferahkaya
article en

Abstract

This study suggests that claudin-5 and beta-catenin may play a role in the pathogenesis of ADHD. These proteins may affect the brain by causing a dysregulation in BBB permeability or through other mechanisms.

Journal of Attention Disorders
İzmir University of Economics (TR), Necmettin Erbakan University (TR), Karamanoğlu Mehmetbey University (TR)
Openalex Percentile: Top 55%
Barrier Structure and Function Studies
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