Maleic acid as a root canal irrigant- a scoping review

7% MA is a potent root canal irrigant with consistent superiority in apical smear layer removal and unique advantages in adhesion and regeneration. Its demineralising effects highlight the need for controlled application, with shorter conditioning times (1-3 min) optimising outcomes while minimising risks. Overall, MA represents a promising, less cytotoxic alternative to EDTA, but standardised clinical protocols and rigorous in vivo validation are essential for its safe integration into endodontic practice.

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Publication Details

Journal
BMC Oral Health
Published
2025-12-08
DOI
https://doi.org/10.1186/s12903-025-07361-9
Primary Topic
Endodontics and Root Canal Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Maleic acid as a root canal irrigant- a scoping review

Edlin Glane Mathias, T. R. Kapur, Nidambur Vasudev Ballal, Arathi Prahallada Rao et al.
BMC Oral Health
Endodontics and Root Canal Treatments
article

Maleic acid as a root canal irrigant- a scoping review

Edlin Glane Mathias, T. R. Kapur, Nidambur Vasudev Ballal, Arathi Prahallada Rao, Sonia Gupta
article en

Abstract

7% MA is a potent root canal irrigant with consistent superiority in apical smear layer removal and unique advantages in adhesion and regeneration. Its demineralising effects highlight the need for controlled application, with shorter conditioning times (1-3 min) optimising outcomes while minimising risks. Overall, MA represents a promising, less cytotoxic alternative to EDTA, but standardised clinical protocols and rigorous in vivo validation are essential for its safe integration into endodontic practice.

BMC Oral HealthVol. 26(1)
Manipal Academy of Higher Education (IN)
Openalex Percentile: Top 46%
Endodontics and Root Canal Treatments
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