Comparison of the efficacy of high-flow nasal cannula with different initial flow settings in patients with acute exacerbations of chronic obstructive pulmonary disease: A systematic review and network meta-analysis
HFNC_Low demonstrates superior efficacy in lowering PaCO₂ levels, the incidence of nasal and facial injuries, and improving pH. Although HFNC_Mod may reduce hospital stay, low-flow settings are recommended as the preferred initial strategy for AECOPD.
Authors
- Longfei Ding (ORCID: https://orcid.org/0000-0002-7660-0876)
- Yuewen He (ORCID: https://orcid.org/0000-0002-4078-5100)
- Tong Wu (ORCID: https://orcid.org/0000-0003-4459-9791)
- Zhengze Zhang (ORCID: https://orcid.org/0009-0006-7939-6731)
- Caineng Wu
- Wuhua Ma
- Hao Liu (ORCID: https://orcid.org/0009-0004-2137-0892)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- First Affiliated Hospital of Guangzhou University of Chinese Medicine (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Pulmonology
- Published
- 2025-12-08
- DOI
- https://doi.org/10.1080/25310429.2025.2598913
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00